neurokinin p — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1087	Substance P	Neurokinin P	Endogenous Metabolite , Neurokinin receptor
	Substance P (Neurokinin P) (SP) is an undecapeptide (a peptide composed of a chain of 11 amino acid residues) member of the tachykinin neuropeptide family.		Endogenous Metabolite , Neurokinin receptor
T7554	Substance P (7-11)	Substance P 7-11(TFA)	Others , Neurokinin receptor
	Substance P (7-11) (Substance P 7-11(TFA)) is a C-terminal fragment of Substance P .		Others , Neurokinin receptor
TP2155	Substance P TFA	Neurokinin P TFA	Others
	Substance P TFA (Neurokinin P TFA) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS, targeting the neurokinin 1 receptor (NK1-receptor, NK1R).		Others
T7828	[Sar9,Met(O2)11]-Substance P	Bhsar-sp,NA	Neurokinin receptor
	[Sar9,Met(O2)11]-Substance P (NA) is an agonist of NK1 receptor.		Neurokinin receptor
T6905	Netupitant	Ro 67-31898/000,CID 6451149	Neurokinin receptor
	Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).		Neurokinin receptor
T7396	Substance P(1-7)	Substance P 1-7	Others , Neurokinin receptor
	Substance P(1-7) (Substance P 1-7) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effects		Others , Neurokinin receptor
T1790	Fosaprepitant dimeglumine	L785298,MK-0517,Fosaprepitant dimeglumine salt	Neurokinin receptor
	Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion...		Neurokinin receptor
T1743	Aprepitant	MK-869,MK-0869,L-754030,Aprepitant`	HIV Protease , Antibacterial , Antibiotic , Neurokinin receptor
	Aprepitant (Aprepitant`) is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and C...
T68068L	(R)-CJ 11974		Neurokinin receptor
	(R)-CJ 11974 is a novel non-peptide neurokinin NK1 substance P receptor antagonist with potential analgesic activity that can be used to study chemotherapy-induced vomiting.		Neurokinin receptor
T25616	Lanepitant 2HCl	LY303870 dihydrochloride,LY 303870 dihydrochloride,LY-303870 dihydrochloride,Lanepitant dihydrochloride	Neurokinin receptor
	Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist with analgesic and anti-inflammatory activity.Lanepitant 2HCl inhibits the binding of Substance P to the neurokinin-1 receptor, inhibits neurogenic inflam...		Neurokinin receptor
T7209	Maropitant		Neurokinin receptor
	Maropitant is a selective neurokinin (NK1) receptor antagonist.		Neurokinin receptor
T3716	Rolapitant	SCH619734	Neurokinin receptor
	Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ...		Neurokinin receptor
T76427	(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B
	(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B functions as a competitive antagonist to the Neurokinin B receptor, exhibiting a pA2 value of 5.5. Notably, it does not affect Substance P or Neurokinin A [1].
T37110	Biotin-Substance P
	Biotin-Substance P acts as a neurotransmitter and neuromodulator in the central nervous system. Neurokinin 1 receptor (NK1R) is the endogenous receptor of Biotin-Substance P.
T13306L2	Vapreotide diacetate
	Vapreotide diacetate is a synthetic analog of somatostatin. It has analgesic activity most likely mediated through the blockade of the neurokinin-1 receptor (NK1R), the substance P (SP)-preferring receptor.
T76429	Neurokinin Receptor (393-407), rat
	Neurokinin Receptor (393-407), rat (SPR393–407), a fragment of the rat neurokinin 1 receptor (NK1R), undergoes rapid endocytosis and subsequent recycling to the plasma membrane upon substance P (SP) binding. This compoun...
T38033	Benzomalvin B
	Benzomalvin B is a fungal metabolite originally isolated from Penicillium. It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P by 24% in vitro when used at a concentration of 100 μ...
T71833	Acetylaszonalenin
	Acetylaszonalenin is a fungal metabolite that has been found in A. flavipes.1 It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P with a Ki value of 170 μM.
T76405	[D-Trp2,7,9] Substance P
	[D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist that exhibits inhibitory affinities (K_i values) of 1 μM for NK-1, 1.3 μM for NK-2, and approximately 9 μM for NK-3 receptors [1].
T76406	[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11)
	[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist that effectively inhibits the actions of gold-protein-substance P (GPSP) and substance P (SP), demonstrating its efficacy in neutralizing t...